2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Na+/HCO3- Cotransporter
  5. Na+/HCO3- Cotransporter Inhibitor

Na+/HCO3- Cotransporter Inhibitor

Na+/HCO3- Cotransporter Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-15529
    S0859
    		Inhibitor 99.74%
    S0859 is a selective, high-affinity generic Na+/HCO3- transporter (NBC) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (Ki=1.7 μM, full inhibition at approximately 30 μM).
  • HY-182767
    SOAT-IN-2
    		Inhibitor
    SOAT-IN-2 is a selective sodium-dependent organic anion transporter (SOAT, SLC10A6) inhibitor. SOAT-IN-2 blocks sodium-dependent cellular uptake of sulfated steroid Dehydroepiandrosterone sulfate (DHEAS, HY-113416). SOAT-IN-2 reduces intracellular estradiol synthesis, DHEA (HY-14650) formation, and DHEAS-stimulated cancer cell proliferation without inducing cytotoxicity. SOAT-IN-2 can be used for the research of breast cancer.